IL-27 enhances LPS-induced IL-1β in human monocytes and murine macrophages
نویسندگان
چکیده
منابع مشابه
IL-27 enhances LPS-induced proinflammatory cytokine production via upregulation of TLR4 expression and signaling in human monocytes.
IL-27, which is produced by activated APCs, bridges innate and adaptive immunity by regulating the development of Th cells. Recent evidence supports a role for IL-27 in the activation of monocytic cells in terms of inflammatory responses. Indeed, proinflammatory and anti-inflammatory activities are attributed to IL-27, and IL-27 production itself is modulated by inflammatory agents such as LPS....
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ژورنال
عنوان ژورنال: Journal of Leukocyte Biology
سال: 2017
ISSN: 0741-5400,1938-3673
DOI: 10.1189/jlb.3a0316-098r